Endogenous retroelements and autoimmune disease
نویسندگان
چکیده
منابع مشابه
Endogenous retroelements and autoimmune disease.
Innate immune sensors of foreign nucleic acids are essential for antiviral immunity, but these same sensors can cause autoimmune disease through inappropriate detection of self-nucleic acids. The sources of the endogenous RNA and DNA that trigger autoreactive responses include chromatin and ribonucleoproteins that are the targets of autoantibodies in numerous autoimmune diseases, including syst...
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ژورنال
عنوان ژورنال: Current Opinion in Immunology
سال: 2012
ISSN: 0952-7915
DOI: 10.1016/j.coi.2012.09.007